Global Fund Partnership Launches Investment Case for Eighth Replenishment

Feb 19, 2025

Yesterday, South Africa co-hosted a virtual launch event for the Global Fund 8th Replenishment Investment Case.

The invetsment case set the fundraising target at $18bn. The Global Fund’s Investment Case shows how to drive impact, save lives and deliver lifesaving tools and resources where they are needed most. Read the Global Fund’s Eighth Replenishment Investment Case in English

Access the Executive Summary in English | Español | Français

Eighth Replenishment Investment Case At a Glance in عربي | 中文 | Deutsch | English | Español | Français | Italiano | 日本語 | 한국어 | Português | Русский

With an investment of US$18 billion, the Global Fund partnership would:

  • Save 23 million lives.
  • Avert 400 million infections or cases.
  • Deliver a return on investment of 1:19, resulting in US$323 billion in returns over 2027-2029.
  • Strengthen health and community systems and enhance pandemic preparedness.
  • Close the equity gaps and accelerate service coverage.
  • Reduce global inequality in life expectancy by 7% between 2023 and 2029.
  • Catalyze improved and more targeted domestic investments for HIV, TB, malaria and health and community systems.
  • Improve resilience to climate change to safeguard progress against HIV, TB and malaria.
  • Save US$42 billion in primary health care costs, bringing the total savings since 2002 to US$145 billion.

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